Paraparetic variant of Guillain-Barré syndrome
Synonyms: Paraparetic variant of GBS
- Type
- Disease
- Group
- Disorder
- Inheritance
- Multigenic/multifactorial, Not applicable
- Age of onset
- All ages
- Status
- active
Paraparetic variant of Guillain-Barré syndrome is a rare variant of Guillain-Barré syndrome characterized by isolated leg weakness, areflexia and radicular leg pain that may simulate a cauda equina or spinal cord syndrome. The arms, ocular, facial, and oropharyngeal muscles are spared, and sphincteric function is normal.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Paraparetic variant of Guillain-Barré syndrome | Paraparetic variant of GBS |
| fr | Variant paraparétique du syndrome de Guillain-Barré | Variant paraparétique du SGB |
| de | Paraparetische Variante des Guillain-Barré-Syndroms | |
| es | Variante paraparética del síndrome de Guillain-Barré | Variante paraparética del GBS |
| it | Variante paraparetica della sindrome di Guillain-Barré | Variante paraparetica di GBS |
| nl | Paraparetische variant van syndroom van Guillain-Barré | Paraparetische variant van GBS |
| pt | Variante paraparética do síndrome Guillain-Barré | |
| pl | Paraparetyczny wariant zespołu Guillaina i Barrégo | Paraparetyczny wariant GBS |
| cs | Paraparetická varianta Guillainova-Barrého syndromu | Paraparetická varianta GBS · Paraparetická varianta Guillain-Barrého syndromu |
| uk | Паралітичний варіант синдрому Гійєна-Барре | Паралітичний варіант GBS |
| zh | 吉兰-巴雷综合征下身轻瘫变体 | GBS下身轻瘫变体 |
| tr | Guillain-Barrè sendromunun paraparetik varyantı | GBS'nin paraparetik varyantı |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | G61.0 | NTBT | attributed | validated |
| ICD-11 | 8C01.0 | NTBT | index | validated |
| MONDO | 0016497 | E | validated | |
| UMLS | C4707803 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:231419Functional variant of Guillain-Barré syndrome
rare neurological diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
2 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Validated | ORPHANET |
| Annual incidence | Unknown | — | Worldwide | Class only | Validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
10 annotations · validated 2018-09-17| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Frequent (79-30%) | ||
| HP:0001284 | Areflexia | |
| HP:0006858 | Impaired distal proprioception | |
| HP:0025459 | Increased CSF/serum albumin ratio | |
| HP:0012531 | Pain | |
| HP:0002385 | Paraparesis | |
| HP:0003477 | Peripheral axonal neuropathy | |
| HP:0011868 | Sciatica | |
| Occasional (29-5%) | ||
| HP:0011948 | Acute respiratory tract infection | |
| HP:0011096 | Peripheral demyelination | |
| Excluded (0%) | ||
| HP:0002839 | Urinary bladder sphincter dysfunction | |
Annotation source: 28514704[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/231445
- This record as JSON: /data/d/231445.json