Neonatal diabetes mellitus
Synonyms: Congenital diabetes mellitus · Diabetes of infancy · Monogenic diabetes of infancy · NDM
- Type
- Clinical group
- Group
- Group of disorders
- Inheritance
- Autosomal dominant, Autosomal recessive, Not applicable
- Age of onset
- Infancy, Neonatal
- Status
- active
A group of rare diabetes mellitus characterized by neonatal diabetes mellitus presents with symptoms including hyperglycemia, failure to thrive and, in some cases, dehydration and ketoacidosis (which can be severe and lead coma), in a child within the first months of life. It encompasses several disorders in which diabetus mellitus may be transient or permanent. It may present as an isolated condition or as part of a syndrome.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Neonatal diabetes mellitus | Congenital diabetes mellitus · Diabetes of infancy · Monogenic diabetes of infancy · NDM |
| fr | Diabète néonatal | |
| de | Diabetes mellitus, neonataler | Diabetes im Säuglings- und Kleinkindalter · Diabetes mellitus, kongenitaler · Monogener Diabetes des Kindesalters · NDM |
| es | Diabetes mellitus neonatal | Diabetes de la infancia · Diabetes mellitus congénita · Diabetes monogénica de la infancia · NDM |
| it | Diabete mellito neonatale | Diabete infantile · Diabete mellito congenito · Diabete monogenico infantile · NDM |
| nl | Neonatale diabetes mellitus | Congenitale diabetes mellitus · Diabetes op zuigelingenleeftijd · Monogenische diabetes op zuigelingenleeftijd · NDM |
| pt | Diabetes mellitus neonatal | Diabetes da infância · Diabetes mellitus congénito · Diabetes monogénico da infância · NDM |
| pl | Cukrzyca noworodków | NDM |
| cs | Novorozenecký diabetes mellitus | NDM |
| uk | Неонатальний цукровий діабет | Вроджений цукровий діабет · Дитячий діабет · Моногенний діабет немовлят · NDM |
| zh | 新生儿糖尿病 | NDM |
| tr | Yenidoğan diabetes mellitusu | NDM |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | P70.2 | E | specific | validated |
| ICD-11 | KB60.2 | E | specific | validated |
| MONDO | 0016391 | E | validated | |
| MONDO | 16391 | E | validated | |
| UMLS | C0158981 | E | validated | |
| MedDRA | 10028933 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (2):
- ORPHA:101952Rare diabetes mellitus
rare endocrine diseases - ORPHA:183625Rare genetic diabetes mellitus
rare genetic diseases
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
5 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Prevalence at birth | 1-9 / 100 000 | 1.1 / 100 000 | Europe | Value and class | Not yet validated | 21953423[PMID]_19499210[PMID]_20546293[PMID] |
| Prevalence at birth | 1-9 / 100 000 | 1.1 / 100 000 | Italy | Value and class | Validated | 21953423[PMID] |
| Prevalence at birth | 1-9 / 100 000 | 1.12 / 100 000 | Germany | Value and class | Validated | 20546293[PMID] |
| Annual incidence | 1-9 / 1 000 000 | 0.62 / 100 000 | Austria | Value and class | Validated | 19496964[PMID] |
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/224
- This record as JSON: /data/d/224.json