Eosinophilic gastroenteritis
Synonyms: EGE · Eosinophilic enteritis · Eosinophilic gastroenterocolitis
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- All ages
- Status
- active
A rare benign gastrointestinal disease characterized by the presence of abnormal and nonspecific gastro-intestinal (GI) manifestations, associated with an eosinophilic infiltration of the GI tract, which can affect several segments and involve several layers within the GI wall.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Eosinophilic gastroenteritis | EGE · Eosinophilic enteritis · Eosinophilic gastroenterocolitis |
| fr | Gastro-entérite à éosinophiles | Entérite éosinophilique · GEE · Gastro-entérite éosinophilique · Gastro-entéro-colite à éosinophiles |
| de | Gastroenteritis, eosinophile | EGE · Eosinophile Enteritis |
| es | Gastroenteritis eosinofílica | EGE · Enteritis eosinofílica · Gastroenterocolitis eosinofílica |
| it | Gastroenterite eosinofila | EGE · Enterite eosinofila · Gastroenterocolite eosinofila |
| nl | Eosinofiele gastro-enteritis | EGE · Eosinofiele enteritis · Eosinofiele gastro-enterocolitis |
| pt | Gastroenterite eosinofílica | |
| pl | Eozynofilowe zapalenie żółądka i jelit | EGE · Eozynofilowe zapalenie jelit |
| cs | Eozinofilní gastroenteritida | EGE · Eozinofilní enteritida · Eozinofilní gastroenterokolitida |
| uk | Еозинофільний гастроентерит | EGE · Еозинофільний ентерит · Еозинофільний гастроентероколіт |
| zh | 嗜酸细胞性胃肠炎 | 嗜酸细胞性胃小肠结肠炎 |
| tr | Eozinofilik gastroenterit | EGE · Eozinofilik enterit · Eozinofilik gastroenterokolit |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | K52.8 | NTBT | attributed | validated |
| ICD-11 | DA94.21 | E | specific | validated |
| MONDO | 0016129 | E | validated | |
| MeSH | C535952 | E | validated | |
| UMLS | C1262481 | E | validated | |
| GARD | 9142 | E | validated | |
| MedDRA | 10017902 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (2):
- ORPHA:402029Primary eosinophilic gastrointestinal disease
rare gastroenterological diseases - ORPHA:101936Rare gastroesophageal disease
rare gastroenterological diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
3 records| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Cases/families | 280 cases | Worldwide | Case(s) | Validated | 11345185[PMID]_23904840[PMID] | |
| Point prevalence | 1-9 / 100 000 | 8.4 / 100 000 | Worldwide | Value and class | Validated | 25988554[PMID]_ORPHANET |
| Point prevalence | 1-9 / 100 000 | — | Europe | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
21 annotations · validated 2016-07-04| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0001880 | Increased total eosinophil count | Diagnostic criterion |
| Frequent (79-30%) | ||
| HP:0002027 | Abdominal pain | Diagnostic criterion |
| HP:0011024 | Abnormality of the gastrointestinal tract | |
| HP:0003193 | Allergic rhinitis | |
| HP:0001903 | Anemia | |
| HP:0002014 | Diarrhea | Diagnostic criterion |
| HP:0002015 | Dysphagia | |
| HP:0011227 | Elevated circulating C-reactive protein concentration | |
| HP:0003073 | Hypoalbuminemia | |
| HP:0001974 | Increased total leukocyte count | |
| HP:0002024 | Malabsorption | |
| HP:0002570 | Steatorrhea | |
| HP:0002013 | Vomiting | Diagnostic criterion |
| Occasional (29-5%) | ||
| HP:0001541 | Ascites | Diagnostic criterion |
| HP:0002099 | Asthma | |
| HP:0001047 | Atopic dermatitis | |
| HP:0000969 | Edema | Diagnostic criterion |
| HP:0003565 | Elevated erythrocyte sedimentation rate | |
| HP:0002573 | Hematochezia | Diagnostic criterion |
| HP:0002243 | Protein-losing enteropathy | |
| HP:0001824 | Weight loss | Diagnostic criterion |
Run the differential on the 1 obligate / very frequent terms
Annotation source: 26770900[PMID]_26358020[PMID]_26075112[PMID]
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/2070
- This record as JSON: /data/d/2070.json