Mixed germ cell tumor
- Type
- Disease
- Group
- Disorder
- Inheritance
- Not applicable
- Age of onset
- Adolescent, Adult, Childhood
- Status
- active
A rare germ cell tumor characterized by composition of two or more malignant germ cell components, the most common combination being dysgerminoma and yolk sac tumor. The tumors typically occur between childhood and young adulthood. They are usually located in the gonads, occasionally also in other regions. Clinical presentation corresponds to the individual germ cell components and the tumor location; manifestations may include abdominal pain, abdominal mass, and menstrual disorder in females, and a testicular mass in males. The most important prognostic factor is tumor stage.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Mixed germ cell tumor | |
| fr | Tumeur germinale maligne mixte | |
| de | Keimzelltumor, gemischter | |
| es | Tumor mixto de células germinales | |
| it | Tumore a cellule germinali miste | |
| nl | Gemengde kiemceltumor | |
| pt | Tumor misto de células germinativas | |
| pl | Mieszany guz germinalny | |
| cs | Smíšený germinální nádor | |
| uk | Змішана герміногенна пухлина | |
| zh | 混合性生殖细胞瘤 | |
| tr | Karma germ hücreli tümör |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | C80.9 | NTBT | attributed | validated |
| ICD-11 | 2D4Y | NTBT | index | validated |
| ICD-11 | XH2PS1 | E | specific | validated |
| MONDO | 0015864 | E | validated | |
| UMLS | C0334524 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:99913Extragonadal non-dysgerminomatous germ cell tumor
rare neoplastic diseases; rare transplant-related disorders
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Annual incidence | <1 / 1 000 000 | 0.01 / 100 000 | Europe | Value and class | Validated | RARECARE surveillance of rare cancers in Europe[OTHER] |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/180234
- This record as JSON: /data/d/180234.json