raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:178320

Acute lung injury

Type
Particular clinical situation in a disease or syndrome
Group
Disorder
Inheritance
Not applicable
Age of onset
All ages
Status
active

Orphadata ships no English definition for this code.

1

Names in Orphadata languages

12 of 12 languages
LangNameSynonyms
enAcute lung injury
frAgression pulmonaire aiguë
deLungenverletzung, akute
esLesión pulmonar aguda
itLesione polmonare acuta
nlAcuut letsel van longAcuut longletsel
ptLesão pulmonar aguda
plOstry uraz płuc
csAkutní plicní poranění
ukГостре пошкодження легень
zh急性肺损伤
trAkut akciğer hasarı
2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-10S27.3NTBTattributedvalidated
ICD-11NB32.3NTBTattributedvalidated
MONDO0015796Evalidated
MeSHD055371Evalidated
UMLSC0242488Evalidated
MedDRA10069351Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

3

Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (1):

No children.

4

Genes

0 direct

Orphanet records no gene directly on this code.

5

Prevalence and incidence

4 records
TypeClassValueAreaQualificationValidationSource
Annual incidence1-5 / 10 00025 / 100 000EuropeValue and classNot yet validated15659944[PMID]_15166842[PMID]
Point prevalence1-5 / 10 000—EuropeClass onlyValidatedEuropean Medicines Agency 2012[OTHER]
Annual incidence1-5 / 10 00025 / 100 000AustraliaValue and classNot yet validated15659944[PMID]_15166842[PMID]
Annual incidence6-9 / 10 00065 / 100 000United StatesValue and classNot yet validated15659944[PMID]_20073554[PMID]_9468178[PMID]

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

6

HPO phenotypes

21 annotations · validated 2020-03-18
HPOTerm (as annotated by Orphanet)Diagnostic
Frequent (79-30%)
HP:0011112Abnormality of serum cytokine level
HP:0002094Dyspnea
HP:0011227Elevated circulating C-reactive protein concentration
HP:0012418Hypoxemia
HP:0030783Increased circulating interleukin 6 concentration
HP:0032094Increased circulating surfactant protein level
HP:0002090Pneumonia
HP:0002113Pulmonary infiltrates
HP:0002098Respiratory distress
HP:0002878Respiratory failure
HP:0002789Tachypnea
Occasional (29-5%)
HP:0006530Abnormal pulmonary interstitial morphology
HP:0011118Abnormality of tumor necrosis factor secretion
HP:0001735Acute pancreatitis
HP:0030955Alcoholism
HP:0025420Diffuse alveolar hemorrhage
HP:0000969Edema
HP:0001945Fever
HP:0002105Hemoptysis
HP:0100806Sepsis
HP:0031273Shock

Annotation source: 27652982[PMID]_22268322[PMID]_25466727[PMID]

7

Sources for this card