Transient hypogammaglobulinemia of infancy
- Type
- Disease
- Group
- Disorder
- Status
- active
A rare primary immunodeficiency characterized by a delay in the maturation of immunoglobulin production, leading to prolongation of the physiologic hypogammaglobulinemia of the newborn period beyond six months of age. Patients present recurrent respiratory infections, otitis media, bronchitis, gastroenteritis, or allergic symptoms in the first two to four years of life, before the condition resolves spontaneously. Some children may remain asymptomatic, and severe or life-threatening infections are rare. The capacity to synthesize specific antibodies in response to vaccines is usually normal.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Transient hypogammaglobulinemia of infancy | |
| fr | Hypoglammaglobulinémie transitoire de l'enfance | |
| de | Transiente Hypogammaglobulinämie der Kindheit | |
| es | Hipogammaglobulinemia transitoria del lactante | |
| it | Ipogammaglobulinemia transitoria dell'infanzia | |
| nl | Transiënte hypogammaglobulinemie op zuigelingenleeftijd | |
| pt | Hipogamaglobulinemia transitória da infância | |
| pl | Przemijająca hipogammaglobulinemia niemowląt | |
| cs | Přechodná hypogamaglobulinémie v dětství | |
| uk | Транзиторна гіпогаммаглобулінемія немовлят | |
| zh | 婴儿一过性低丙种球蛋白血症 | |
| tr | Süt çocuğunda geçici hipogammaglobulinemi |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| ICD-10 | D80.7 | E | specific | validated |
| ICD-11 | 4A01.03 | E | specific | validated |
| MONDO | 0015698 | E | validated | |
| UMLS | C0272238 | E | validated | |
| MedDRA | 10044388 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (1):
- ORPHA:331232Immunodeficiency with isotype or light chain deficiencies with normal number of B-cells
rare genetic diseases; rare immunological diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
0 recordsNo prevalence record in this release.
HPO phenotypes
Orphanet has no HPO annotation for this code in this release.
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/169139
- This record as JSON: /data/d/169139.json