Loose anagen syndrome
- Type
- Disease
- Group
- Disorder
- Inheritance
- Autosomal dominant
- Age of onset
- Childhood
- Status
- active
Loose anagen syndrome is a rare benign hair disorder affecting predominantly blond females in childhood and characterized by the presence of hair that can be easily and painlessly pulled out. Most of the hair is in the anagen phase and lacks an external epithelial sheath. Hair grows back quickly and the condition improves spontaneously with aging. Loose anagen hair can be associated with other anomalies, such as coloboma.
Names in Orphadata languages
12 of 12 languages| Lang | Name | Synonyms |
|---|---|---|
| en | Loose anagen syndrome | |
| fr | Maladie des cheveux anagènes caducs | |
| de | Lose Anagenhaar-Syndrom | |
| es | Síndrome del cabello anágeno suelto | |
| it | Sindrome dei capelli caduchi in anagen | |
| nl | Loose anagen-syndroom | |
| pt | Síndrome do cabelo em fase anágena | |
| pl | Zespół luźnych włosów anagenowych | Coloboma - nieprawidłowe włosy |
| cs | Syndrom se snadno vypadávajícími vlasy v anagenní fázi | |
| uk | Синдром укороченого анагена | |
| zh | 生长期毛发松动综合征 | |
| tr | Gevşek anajen sendromu |
Definition in:
Cross-references
qualifier = Orphanet mapping relation| Source | Code | Qualifier | ICD relation | Validation |
|---|---|---|---|---|
| OMIM | 600628 | E | validated | |
| ICD-10 | L65.1 | NTBT | attributed | validated |
| ICD-11 | EC21.0 | NTBT | index | validated |
| MONDO | 0010908 | E | validated | |
| MeSH | D058247 | E | validated | |
| UMLS | C0406468 | E | validated | |
| GARD | 3287 | E | validated | |
| MedDRA | 10085066 | E | validated |
E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.
Classification
Preferential parent (Orphanet linearisation):
Parents in the classifications (2):
- ORPHA:79364Alopecia
rare skin diseases - ORPHA:481771Genetic alopecia
rare genetic diseases
No children.
Genes
0 directOrphanet records no gene directly on this code.
Prevalence and incidence
1 record| Type | Class | Value | Area | Qualification | Validation | Source |
|---|---|---|---|---|---|---|
| Point prevalence | Unknown | — | Worldwide | Class only | Not yet validated | ORPHANET |
Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.
HPO phenotypes
3 annotations · validated 2016-06-01| HPO | Term (as annotated by Orphanet) | Diagnostic |
|---|---|---|
| Very frequent (99-80%) | ||
| HP:0010721 | Abnormal hair whorl | |
| HP:0001595 | Abnormality of the hair | |
| Frequent (79-30%) | ||
| HP:0000612 | Iris coloboma | |
Run the differential on the 2 obligate / very frequent terms
Sources for this card
- Orphanet page: orpha.net/en/disease/detail/168
- This record as JSON: /data/d/168.json