raremaprare-disease reference indexOrphadata 2026-06-23 · HPO 2026-09-01
ORPHA:1546

Cryptococcosis

Type
Disease
Group
Disorder
Inheritance
Not applicable
Age of onset
All ages
Status
active

A cosmopolitan fungal infection due to <i>Cryptococcus neoformans</i>.

1

Names in Orphadata languages

12 of 12 languages
LangNameSynonyms
enCryptococcosis
frCryptococcose
deKryptokokkose
esCriptococosis
itCriptococcosi
nlCryptokokkose
ptCriptococose
plKryptokokoza
csKryptokokóza
ukКриптококоз
zh隐球菌病
trKriptokokoz

Definition in:

2

Cross-references

qualifier = Orphanet mapping relation
SourceCodeQualifierICD relationValidation
ICD-10B45.0BTNTspecificvalidated
ICD-10B45.1BTNTspecificvalidated
ICD-10B45.2BTNTspecificvalidated
ICD-10B45.3BTNTspecificvalidated
ICD-10B45.7BTNTspecificvalidated
ICD-10B45.8BTNTspecificvalidated
ICD-10B45.9BTNTspecificvalidated
ICD-111F27Especificvalidated
ICD-111F27.0BTNTspecificvalidated
ICD-111F27.1BTNTspecificvalidated
ICD-111F27.2BTNTspecificvalidated
ICD-111F27.YBTNTattributedvalidated
MONDO0005724Evalidated
MeSHD003453Evalidated
UMLSC0010414Evalidated
GARD6218Evalidated
MedDRA10011490Evalidated

E exact · NTBT this ORPHAcode is narrower than the target · BTNT broader than the target · ND not decided.

3

Classification

Preferential parent (Orphanet linearisation):

Parents in the classifications (1):

No children.

4

Genes

0 direct

Orphanet records no gene directly on this code.

5

Prevalence and incidence

2 records
TypeClassValueAreaQualificationValidationSource
Annual incidence1-5 / 10 00011 / 100 000EuropeValue and classValidated[EXPERT]
Point prevalenceUnknown—WorldwideClass onlyValidatedORPHANET

Value is Orphadata's ValMoy: the mean estimate per 100 000 for prevalence and incidence, the number of cases or families for case reports.

6

HPO phenotypes

42 annotations · validated 2019-10-28
HPOTerm (as annotated by Orphanet)Diagnostic
Frequent (79-30%)
HP:0012735Cough
HP:0001945Fever
HP:0002721Immunodeficiency
HP:0025392Nodular pattern on pulmonary HRCT
Occasional (29-5%)
HP:0000478Abnormality of the eye
HP:0000504Abnormality of vision
HP:0000708Atypical behavior
HP:0002960Autoimmunity
HP:0002120Cerebral cortical atrophy
HP:0100749Chest pain
HP:0001394Cirrhosis
HP:0002094Dyspnea
HP:0002315Headache
HP:0000238Hydrocephalus
HP:0002516Increased intracranial pressure
HP:0003690Limb muscle weakness
HP:0100721Mediastinal lymphadenopathy
HP:0001287Meningitis
HP:0001268Mental deterioration
HP:0002664Neoplasm
HP:0031179Nuchal rigidity
HP:0002202Pleural effusion
HP:0002090Pneumonia
HP:0002098Respiratory distress
HP:0002725Systemic lupus erythematosus
HP:0002013Vomiting
Very rare (<4-1%)
HP:0001291Abnormal cranial nerve morphology
HP:0000587Abnormal optic nerve morphology
HP:0000479Abnormal retinal morphology
HP:0000356Abnormality of the outer ear
HP:0000618Blindness
HP:0002181Cerebral edema
HP:0005526Lymphoid leukemia
HP:0002354Memory impairment
HP:0000602Ophthalmoplegia
HP:0002797Osteolysis
HP:0002754Osteomyelitis
HP:0002586Peritonitis
HP:0000024Prostatitis
HP:0001250Seizure
HP:0100806Sepsis
HP:0011531Vitritis

Annotation source: 31578566[PMID]_31587180[PMID]_29738314[PMID]_26897067[PMID]

7

Sources for this card